Stadium: The Buc Dome
Home Manager: Alaura Sharp Away Manager: Clarisse Garcia
| WNCAAB | 2022/02/05 20:00 | Presbyterian (W) v Charleston Southern (W) | W | 60-49 |
| WNCAAB | 2022/01/12 23:00 | Charleston Southern (W) v Presbyterian (W) | W | 58-68 |
| WNCAAB | 2021/01/05 23:00 | Charleston Southern (W) v Presbyterian (W) | L | 66-63 |
| WNCAAB | 2021/01/05 00:00 | Presbyterian (W) v Charleston Southern (W) | W | 62-51 |
| WNCAAB | 2020/02/15 19:00 | Presbyterian (W) v Charleston Southern (W) | W | 76-53 |
| WNCAAB | 2020/01/29 00:00 | Charleston Southern (W) v Presbyterian (W) | W | 46-67 |
| WNCAAB | 2019/02/02 19:00 | Presbyterian (W) v Charleston Southern (W) | L | 55-63 |
| WNCAAB | 2018/03/03 20:00 | Charleston Southern (W) v Presbyterian (W) | W | 58-81 |
| WNCAAB | 2022/03/03 17:00 | Campbell (W) v Presbyterian (W) | L | 59-56 |
| WNCAAB | 2022/03/01 17:00 | Presbyterian (W) v Winthrop (W) | W | 65-60 |
| WNCAAB | 2022/02/26 19:00 | Presbyterian (W) v Radford (W) | W | 61-57 |
| WNCAAB | 2022/02/22 23:00 | Gardner Webb Women v Presbyterian (W) | W | 58-72 |
| WNCAAB | 2022/02/19 20:00 | Presbyterian (W) v Longwood (W) | L | 63-76 |
| WNCAAB | 2022/02/16 23:00 | USC Upstate (W) v Presbyterian (W) | L | 80-67 |
| WNCAAB | 2022/02/15 23:00 | Presbyterian (W) v USC Upstate (W) | L | 66-68 |
| WNCAAB | 2022/02/12 19:00 | North Carolina A&T (W) v Presbyterian (W) | L | 73-56 |
| WNCAAB | 2022/03/01 19:00 | High Point (W) v Charleston Southern (W) | L | 54-34 |
| WNCAAB | 2022/02/26 19:00 | Charleston Southern (W) v UNC Asheville Women | L | 43-63 |
| WNCAAB | 2022/02/23 23:00 | North Carolina A&T (W) v Charleston Southern (W) | L | 76-42 |
| WNCAAB | 2022/02/19 19:00 | Charleston Southern (W) v High Point (W) | L | 50-71 |
| WNCAAB | 2022/02/17 22:30 | High Point (W) v Charleston Southern (W) | L | 69-60 |
| WNCAAB | 2022/02/15 23:00 | Winthrop (W) v Charleston Southern (W) | L | 56-43 |
| WNCAAB | 2022/02/12 19:00 | Charleston Southern (W) v Campbell (W) | L | 52-63 |
| WNCAAB | 2022/02/09 23:00 | Gardner Webb Women v Charleston Southern (W) | L | 90-51 |