Stadium: Greensboro Coliseum Round: 122
Home Manager: Jeff Capel Away Manager: T.J. Otzelberger
| NCAAB | 2022/03/08 19:00 | Boston College v Pittsburgh | L | 66-46 |
| NCAAB | 2022/03/05 19:30 | Pittsburgh v Notre Dame | L | 54-78 |
| NCAAB | 2022/03/02 01:00 | Duke v Pittsburgh | L | 86-56 |
| NCAAB | 2022/02/23 01:00 | Miami Florida v Pittsburgh | L | 85-64 |
| NCAAB | 2022/02/20 00:00 | Georgia Tech v Pittsburgh | L | 68-62 |
| NCAAB | 2022/02/17 01:00 | Pittsburgh v North Carolina | W | 76-67 |
| NCAAB | 2022/02/12 20:00 | NC State v Pittsburgh | W | 69-71 |
| NCAAB | 2022/02/10 02:00 | Pittsburgh v Florida State | W | 56-51 |
| NCAAB | 2022/03/26 01:59 | Iowa State v Miami Florida | L | 56-70 |
| NCAAB | 2022/03/20 22:10 | Iowa State v Wisconsin | W | 54-49 |
| NCAAB | 2022/03/18 23:57 | Iowa State v LSU | W | 59-54 |
| NCAAB | 2022/03/11 02:30 | Iowa State v Texas Tech | L | 41-72 |
| NCAAB | 2022/03/05 23:00 | Iowa State v Baylor Bears | L | 68-75 |
| NCAAB | 2022/03/03 00:00 | Oklahoma State v Iowa State | L | 53-36 |
| NCAAB | 2022/02/26 19:00 | Iowa State v Kansas State | W | 74-73 |
| NCAAB | 2022/02/24 00:00 | West Virginia v Iowa State | W | 81-84 |